Ephesians Prysock is joining Carver Willis in San Francisco.The former Washington Huskies corner was selected by the San Francisco 49ers in the fourth round of the NFL Draft on Saturday, coming off the board with the 139th overall selection.Prysock had been connected to the 49ers throughout the process, with one source telling Huskies Wire at Washington's pro day that San Francisco was high on him as a player.DBU keeps shipping. Pro Dawg. Congrats Ephe @ephe5ian5pic.twitter.com/KZOP3wvDdK— Washington Football (@UW_Football) April 25, 2026A two-year starter at Washington after transferring in from Arizona, Prysock had 48 tackles, 8 pass deflections, and an interception as a senior in 2025.
Across his career, he had 170 tackles, 2 tackles for loss, 1 forced fumble, 21 pass deflections, and 2 interceptions while playing for head coach Jedd Fisch.Prysock shocked most people when he ran a 4.45 40-yard dash at 6-foot-3 at the NFL Combine in Indianapolis. That blend of size and speed is an appealing combination for many NFL teams, plus Prysock has played on punt coverage all four years and should contribute on special teams right away in the NFL.While he struggled with penalties - 6 in 2025 - and converting interceptions, Prysock is a durable and physical player who plays with good awareness in zone coverage.
He will likely step in as the 49ers' CB3 behind Renardo Green and Deommodore Lenoir.The Athletic's Dane Brugler had this to say about Prysock in his draft guide, The Beast: "Prysock has rare physical traits that are hard to find at the position, although he is still learning how to maximize those tools in coverage. He will appeal to both press-heavy and zone-based schemes as a developmental dart throw."This article originally appeared on Huskies Wire: Washington Huskies CB Ephesians Prysock drafted by San Francisco 49ers